Scientist I, Upstream Process Development (Viral Vector Services)

As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.

Location/Division Specific Information

At Viral Vector Services (VVS) a division of Thermo Fisher Scientific we deliver, from process development through commercial supply, we offer the expertise and resources vital to help clients deliver innovative gene therapies. Placed in the forefront of our leading- and innovative Cell and Gene Therapy business enabling clients to cure genetic, rare, and otherwise untreatable diseases.

Location: 5 Commerce Boulevard Plainville, MA
Shift: M-F 8am-4:30pm (A flexible work schedule may be required including weekends and evenings as needed to complete client work.)
Note: Rotating schedule starts once plant is in production

How will you make an impact?

As a member of the Upstream Process Development team, you will have the opportunity to learn to operate cutting-edge instruments and perform activities spanning the full cell line and cell culture production process. This is a hands-on bench scientist position. The ideal candidate shall have excellent lab skills, strong documentation skills, demonstrated ability to analyze and interpret data to draw conclusions and make recommendations, and strong collaboration and teamwork skills.

As a member of the Process Development team, you will work with project leads to support the successful execution of experiments and technical transfer activities. This will include supporting the technical transfer process assessments, Pilot Plant activities and transfer into cGMP manufacturing. This will also include late-phase process characterization of viral vector manufacturing processes.

What you will do...

• Help conduct experiments for development activities.
• Complete experimental protocols / work instructions accurately and with limited supervision.
• Record results in notebook accurately, clearly, and regularly.
• Prepare experiments/data for presentation.
• Prepare and/or review run execution documents such as SOPs and protocols
• Participate in the development and/or optimization and implementation of new processes in the PD laboratory.
• Actively participate in laboratory instrumentation and equipment preventative maintenance and qualification programs.
• Demonstrate a strong focus on continuous improvement.
• Perform daily lab cleaning, preventative maintenance of equipment, ordering of supplies, and autoclaving of manifolds.
• Complete improvement projects identified.
• Identify process bottlenecks and work closely with process development SMEs to solve process challenges.
• Support execution of analytical testing for process and product development/characterization.

How you will get there...

Education

• Bachelor’s Degree in biology, chemistry, biochemistry, (bio)chemical engineering, biomedical engineering, or a related field.

Experience

• 1+ years’ experience in a process development / manufacturing environment preferred

Knowledge, Skills, Abilities

• Industry experience in aseptic technique, cell culture, single-use bioreactors (SUBs), wave reactors preferred.
• Demonstrated knowledge of cGMPs/GLP or regulatory affairs pertaining to the pharmaceutical and biological industries is preferred.
• Knowledge of gene therapy product and/or process development preferred.
• Excellent problem solving and critical thinking skills, including strong attention to detail.
• Advise supervisor of factors that may affect quality, accuracy, timeliness, and usefulness of data.
• Excellent organization, planning, and time management skills.
• Self-motivated, willing to learn, independent and a proactive driving force of efficient execution.
• Strong interpersonal and communications skills (written and oral).
• Able to work effectively with a wide range of constituencies in a diverse environment.
• Good comprehension of Microsoft Office Suite software.
• A flexible work schedule may be required including weekends and evenings as needed to complete client work.
• Must be fluent in English

At Thermo Fisher Scientific, each one of our 120,000+ extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner, and safer.

Apply today! http://jobs.thermofisher.com

“We offer competitive remuneration, annual incentive plan bonus scheme, healthcare, company pension, and a range of employee benefits!Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation.”

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